While imbuing and infusing gems can be useful to raise your stats, many decisions come down to a personal preference.
Here are a few of my most successful combinations, with possible alternatives in italics:
The only way I've been able to make two imbues add to the same stat is by using a "+1" after a "+2 or more"
Here is a list of useful imbues:
abalone bloodtoken: +3 str
egg bloodtoken: +1 str +2 stam
bark bloodtoken: +5 attack rating
bloodstone fetish: +health -mana
wood bloodtoken: +1 str +2 agil
turquoise charm: +1 agi +2 coor
coral icon: +5 wis -2 intel
deadwood idol: +2 wis +1 stam
skullgem fetish: +5 intelligence +2 wisdom -5 stamina
moonstone charm: +1 wis +1 intel +1 coor